7RH2
IRF4 Transcription factor mutant -K59R
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, G, H (A, B, G, H) | ICSAT transcription factor | polymer | 111 | 13132.8 | 4 | UniProt (Q99419) Pfam (PF00605) UniProt (by SIFTS) (Q15306) | Homo sapiens (Human) | |
| 2 | C, D (C, D) | DNA (5'-D(*CP*AP*AP*CP*TP*GP*AP*AP*AP*CP*CP*GP*AP*GP*AP*AP*AP*GP*C)-3') | polymer | 19 | 5840.8 | 2 | Homo sapiens | ||
| 3 | E, F (E, F) | DNA (5'-D(*GP*CP*TP*TP*TP*CP*TP*CP*GP*GP*TP*TP*TP*CP*AP*GP*TP*TP*G)-3') | polymer | 19 | 5808.7 | 2 | Homo sapiens | ||
| 4 | I, J, K, L, M (A, B, D, F, H) | water | water | 18.0 | 13 | Chemie (HOH) |
Sequence modifications
A, B, G, H: 21 - 129 (UniProt: Q99419)
| PDB | External Database | Details |
|---|---|---|
| Gly 19 | - | expression tag |
| Ser 20 | - | expression tag |
| Arg 59 | Lys 90 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 75830.5 | |
| All* | Total formula weight | 75830.5 |
