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7RH2

IRF4 Transcription factor mutant -K59R

Functional Information from GO Data
ChainGOidnamespacecontents
A0000976molecular_functiontranscription cis-regulatory region binding
A0003700molecular_functionDNA-binding transcription factor activity
A0006355biological_processregulation of DNA-templated transcription
B0000976molecular_functiontranscription cis-regulatory region binding
B0003700molecular_functionDNA-binding transcription factor activity
B0006355biological_processregulation of DNA-templated transcription
G0000976molecular_functiontranscription cis-regulatory region binding
G0003700molecular_functionDNA-binding transcription factor activity
G0006355biological_processregulation of DNA-templated transcription
H0000976molecular_functiontranscription cis-regulatory region binding
H0003700molecular_functionDNA-binding transcription factor activity
H0006355biological_processregulation of DNA-templated transcription
Functional Information from PROSITE/UniProt
site_idPS00601
Number of Residues34
DetailsIRF_1 IRF tryptophan pentad repeat DNA-binding domain signature. WeNeeksiFrIPWkHagrqdynreeDaaLFKaWA
ChainResidueDetails
ATRP42-ALA75

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues432
DetailsDNA_BIND: IRF tryptophan pentad repeat => ECO:0000255|PROSITE-ProRule:PRU00840
ChainResidueDetails
AASN21-PRO129
BASN21-PRO129
GASN21-PRO129
HASN21-PRO129

227111

PDB entries from 2024-11-06

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