7R5L
Crystal structure of YTHDF2 with compound YLI_DC1_015
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | YTH domain-containing family protein 2 | polymer | 167 | 19367.8 | 1 | UniProt (Q9Y5A9) Pfam (PF04146) In PDB | Homo sapiens (human) | CLL-associated antigen KW-14,High-glucose-regulated protein 8,Renal carcinoma antigen NY-REN-2 |
2 | A | 3,6-dimethyl-2~{H}-1,2,4-triazin-5-one | non-polymer | 125.1 | 1 | Chemie (I4S) | |||
3 | A | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
4 | water | water | 18.0 | 141 | Chemie (HOH) |
Sequence modifications
A: 408 - 552 (UniProt: Q9Y5A9)
PDB | External Database | Details |
---|---|---|
Met 386 | - | initiating methionine |
Gly 387 | - | expression tag |
Ser 388 | - | expression tag |
Ser 389 | - | expression tag |
Tyr 390 | - | expression tag |
His 391 | - | expression tag |
His 392 | - | expression tag |
His 393 | - | expression tag |
His 394 | - | expression tag |
His 395 | - | expression tag |
His 396 | - | expression tag |
Ser 397 | - | expression tag |
Ser 398 | - | expression tag |
Gly 399 | - | expression tag |
Glu 400 | - | expression tag |
Asn 401 | - | expression tag |
Leu 402 | - | expression tag |
Tyr 403 | - | expression tag |
Phe 404 | - | expression tag |
Gln 405 | - | expression tag |
His 406 | - | expression tag |
Met 407 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 19367.8 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 605.4 | |
All* | Total formula weight | 19973.3 |