7R3A

Crystal structure of S-adenosyl-L-homocysteine hydrolase from Methanococcus maripaludis in complex with inosine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	S-inosyl-L-homocysteine hydrolase	polymer	435	48061.8	8	UniProt (Q6LYR8) Pfam (PF05221) Pfam (PF00670)	Methanococcus maripaludis	SIHH
2	BA, EA, I, L, O... (G, H, A, B, C...)	INOSINE	non-polymer		268.2	8	Chemie (NOS)
3	CA, FA, J, M, P... (G, H, A, B, C...)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	8	Chemie (NAD)
4	AA, DA, K, N, Q... (G, H, A, B, C...)	TETRAETHYLENE GLYCOL	non-polymer		194.2	8	Chemie (PG4)
5	GA, HA, IA, JA, KA... (A, B, C, D, E...)	water	water		18.0	94	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 21 - 435 (UniProt: Q6LYR8)

PDB	External Database	Details
Met 1	-	initiating methionine
Gly 2	-	expression tag
Ser 3	-	expression tag
Ser 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
Ser 11	-	expression tag
Ser 12	-	expression tag
Gly 13	-	expression tag
Leu 14	-	expression tag
Val 15	-	expression tag
Pro 16	-	expression tag
Arg 17	-	expression tag
Gly 18	-	expression tag
Ser 19	-	expression tag
His 20	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	384494.5
Non-Polymers*	Number of molecules	24
	Total formula weight	9007.0
All*	Total formula weight	393501.5

*Water molecules are not included.