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7R3A

Crystal structure of S-adenosyl-L-homocysteine hydrolase from Methanococcus maripaludis in complex with inosine

Functional Information from GO Data
ChainGOidnamespacecontents
A0004013molecular_functionadenosylhomocysteinase activity
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006556biological_processS-adenosylmethionine biosynthetic process
A0016802molecular_functiontrialkylsulfonium hydrolase activity
A0033353biological_processL-methionine cycle
B0004013molecular_functionadenosylhomocysteinase activity
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006556biological_processS-adenosylmethionine biosynthetic process
B0016802molecular_functiontrialkylsulfonium hydrolase activity
B0033353biological_processL-methionine cycle
C0004013molecular_functionadenosylhomocysteinase activity
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0006556biological_processS-adenosylmethionine biosynthetic process
C0016802molecular_functiontrialkylsulfonium hydrolase activity
C0033353biological_processL-methionine cycle
D0004013molecular_functionadenosylhomocysteinase activity
D0005737cellular_componentcytoplasm
D0005829cellular_componentcytosol
D0006556biological_processS-adenosylmethionine biosynthetic process
D0016802molecular_functiontrialkylsulfonium hydrolase activity
D0033353biological_processL-methionine cycle
E0004013molecular_functionadenosylhomocysteinase activity
E0005737cellular_componentcytoplasm
E0005829cellular_componentcytosol
E0006556biological_processS-adenosylmethionine biosynthetic process
E0016802molecular_functiontrialkylsulfonium hydrolase activity
E0033353biological_processL-methionine cycle
F0004013molecular_functionadenosylhomocysteinase activity
F0005737cellular_componentcytoplasm
F0005829cellular_componentcytosol
F0006556biological_processS-adenosylmethionine biosynthetic process
F0016802molecular_functiontrialkylsulfonium hydrolase activity
F0033353biological_processL-methionine cycle
G0004013molecular_functionadenosylhomocysteinase activity
G0005737cellular_componentcytoplasm
G0005829cellular_componentcytosol
G0006556biological_processS-adenosylmethionine biosynthetic process
G0016802molecular_functiontrialkylsulfonium hydrolase activity
G0033353biological_processL-methionine cycle
H0004013molecular_functionadenosylhomocysteinase activity
H0005737cellular_componentcytoplasm
H0005829cellular_componentcytosol
H0006556biological_processS-adenosylmethionine biosynthetic process
H0016802molecular_functiontrialkylsulfonium hydrolase activity
H0033353biological_processL-methionine cycle
Functional Information from PROSITE/UniProt
site_idPS00738
Number of Residues15
DetailsADOHCYASE_1 S-adenosyl-L-homocysteine hydrolase signature 1. GCNpLSTQDdVAAAC
ChainResidueDetails
AGLY93-CYS107

site_idPS00739
Number of Residues18
DetailsADOHCYASE_2 S-adenosyl-L-homocysteine hydrolase signature 2. GKnvvVgGYGwCGRGvaS
ChainResidueDetails
AGLY225-SER242

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues128
DetailsBinding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00563","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

254587

PDB entries from 2026-06-03

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