7QNW
The receptor binding domain of SARS-CoV-2 Omicron variant spike glycoprotein in complex with Beta-55 and EY6A Fabs
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | H | EY6A heavy chain | polymer | 226 | 24346.3 | 1 | Homo sapiens (Human) | ||
2 | L | EY6A light chain | polymer | 215 | 23315.9 | 1 | Homo sapiens (Human) | ||
3 | E | Surface glycoprotein | polymer | 202 | 23157.2 | 1 | UniProt (A0A7U3CI26) Pfam (PF09408) UniProt (by SIFTS) (P0DTC2) In PDB | Severe acute respiratory syndrome coronavirus 2 | |
4 | A | Beta-55 heavy chain | polymer | 232 | 24895.9 | 1 | Homo sapiens (Human) | ||
5 | B | Beta-55 light chain | polymer | 215 | 23491.2 | 1 | Homo sapiens (Human) | ||
6 | C | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
7 | L, E, A, B | GLYCEROL | non-polymer | 92.1 | 9 | Chemie (GOL) | |||
8 | E, A | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
9 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
10 | water | water | 18.0 | 102 | Chemie (HOH) |
Sequence modifications
E: 333 - 528 (UniProt: A0A7U3CI26)
PDB | External Database | Details |
---|---|---|
His 327 | - | expression tag |
His 328 | - | expression tag |
His 329 | - | expression tag |
His 330 | - | expression tag |
His 331 | - | expression tag |
His 332 | - | expression tag |
Asp 339 | Gly 16 | variant |
Leu 371 | Ser 48 | variant |
Pro 373 | Ser 50 | variant |
Phe 375 | Ser 52 | variant |
Lys 440 | Asn 117 | conflict |
Ser 446 | Gly 123 | variant |
Asn 477 | Ser 154 | conflict |
Lys 478 | Thr 155 | variant |
Ala 484 | Lys 161 | conflict |
Arg 493 | Gln 170 | conflict |
Ser 496 | Gly 173 | conflict |
Arg 498 | Gln 175 | variant |
His 505 | Tyr 182 | conflict |
Lys 527 | Pro 204 | variant |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 119206.4 | |
Branched | Number of molecules | 1 |
Total formula weight | 424.4 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 982.4 | |
All* | Total formula weight | 120613.2 |