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7Q3Y

Structure of full-length, monomeric, soluble somatic angiotensin I-converting enzyme showing the N- and C-terminal ellipsoid domains

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Angiotensin-converting enzymepolymer1211139614.01UniProt (P12821)
Pfam (PF01401)
Homo sapiens (Human)ACE,Dipeptidyl carboxypeptidase I,Kininase II
2B
(B)
alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched748.71In PDB
GlyTouCan (G22573RC)
3C, D
(C, D)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.42In PDB
GlyTouCan (G42666HT)
4E, G, H, I
(E, G, H, I)
beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched586.54In PDB
GlyTouCan (G15407YE)
5F
(F)
alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched910.81In PDB
GlyTouCan (G22768VO)
6J
(J)
alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranosebranched1057.01In PDB
GlyTouCan (G82348BZ)
7K
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
8L
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
9M, N, O, P
(A)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.24Chemie (NAG)
10Q
(A)
waterwater18.01Chemie (HOH)
Sequence modifications
A: 1 - 1211 (UniProt: P12821)
PDBExternal DatabaseDetails
Leu 576Pro 605engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight139614.0
BranchedNumber of molecules9
Total formula weight5911.4
Non-Polymers*Number of molecules6
Total formula weight985.7
All*Total formula weight146511.1
*Water molecules are not included.

227933

PDB entries from 2024-11-27

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