7Q3P
Crystal structure of IgG1-Fc-MST-HN (efgartigimod)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | IgG1-Fc-MST-HN | polymer | 225 | 25492.8 | 3 | Pfam (PF07654) UniProt (by SIFTS) (P01857) | Homo sapiens | |
| 2 | D, G (D, G) | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 2 | In PDB GlyTouCan (G86851RC) | |||
| 3 | E (E) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G43381RC) | |||
| 4 | F, I (F, I) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose | branched | 383.3 | 2 | In PDB GlyTouCan (G85856KC) | |||
| 5 | H (H) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 707.6 | 1 | In PDB GlyTouCan (G32791GB) | |||
| 6 | J, K, O, P (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 7 | L (B) | beta-D-mannopyranose | non-polymer | 180.2 | 1 | Chemie (BMA) | |||
| 8 | M, N (B) | alpha-D-mannopyranose | non-polymer | 180.2 | 2 | Chemie (MAN) | |||
| 9 | Q (B) | alpha-L-fucopyranose | non-polymer | 164.2 | 1 | Chemie (FUC) | |||
| 10 | R, S, T (A, B, C) | water | water | 18.0 | 461 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 76478.5 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 2957.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1589.5 | |
| All* | Total formula weight | 81025.7 |
