7Q3P
Crystal structure of IgG1-Fc-MST-HN (efgartigimod)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | IgG1-Fc-MST-HN | polymer | 225 | 25492.8 | 3 | Pfam (PF07654) UniProt (by SIFTS) (P01857) In PDB | Homo sapiens | |
2 | D, G | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 2 | In PDB GlyTouCan (G86851RC) | |||
3 | E | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G43381RC) | |||
4 | F, I | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose | branched | 383.3 | 2 | In PDB GlyTouCan (G85856KC) | |||
5 | H | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 707.6 | 1 | In PDB GlyTouCan (G32791GB) | |||
6 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
7 | B | beta-D-mannopyranose | non-polymer | 180.2 | 1 | Chemie (BMA) | |||
8 | B | alpha-D-mannopyranose | non-polymer | 180.2 | 2 | Chemie (MAN) | |||
9 | B | alpha-L-fucopyranose | non-polymer | 164.2 | 1 | Chemie (FUC) | |||
10 | water | water | 18.0 | 461 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 76478.5 | |
Branched | Number of molecules | 6 |
Total formula weight | 2957.7 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1589.5 | |
All* | Total formula weight | 81025.7 |