7PWY
Structure of human dimeric ACMSD in complex with the inhibitor TES-1025
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase | polymer | 336 | 38084.2 | 4 | UniProt (Q8TDX5) Pfam (PF04909) | Homo sapiens (human) | Picolinate carboxylase, alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase |
| 2 | E, I, M, O (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | F, J (A, B) | 2-[3-[(5-cyano-6-oxidanylidene-4-thiophen-2-yl-1H-pyrimidin-2-yl)sulfanylmethyl]phenyl]ethanoic acid | non-polymer | 383.4 | 2 | Chemie (8EK) | |||
| 4 | G, H, K, L, N... (A, B, C, D) | POTASSIUM ION | non-polymer | 39.1 | 6 | Chemie (K) | |||
| 5 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 289 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 152336.9 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1263.1 | |
| All* | Total formula weight | 153600.0 |
