7NX4
Crystal structure of the TG and EGF-like domains of ALK
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ALK tyrosine kinase receptor | polymer | 389 | 40499.7 | 1 | UniProt (Q9UM73) Pfam (PF12810) | Homo sapiens (Human) | Anaplastic lymphoma kinase |
| 2 | B, C, D, E (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 3 | F (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | G, H (A) | NICKEL (II) ION | non-polymer | 58.7 | 2 | Chemie (NI) |
Sequence modifications
A: 648 - 1030 (UniProt: Q9UM73)
| PDB | External Database | Details |
|---|---|---|
| Gly 1031 | - | expression tag |
| Thr 1032 | - | expression tag |
| Asp 1033 | - | expression tag |
| Glu 1034 | - | expression tag |
| Val 1035 | - | expression tag |
| Asp 1036 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40499.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1067.6 | |
| All* | Total formula weight | 41567.3 |
