7NX3
Crystal structure of ALK in complex with Fab324
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F (A, F) | ALK tyrosine kinase receptor | polymer | 389 | 40499.7 | 2 | UniProt (Q9UM73) Pfam (PF12810) | Homo sapiens (Human) | Anaplastic lymphoma kinase |
| 2 | B, E (B, E) | Fab324 HeavyChain | polymer | 231 | 24516.2 | 2 | Mus musculus | ||
| 3 | C, D (C, D) | Fab324 Light Chain | polymer | 218 | 23918.4 | 2 | Mus musculus | ||
| 4 | G, H, I, J, K... (A, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 8 | Chemie (NAG) |
Sequence modifications
A, F: 648 - 1030 (UniProt: Q9UM73)
| PDB | External Database | Details |
|---|---|---|
| Gly 1031 | - | expression tag |
| Thr 1032 | - | expression tag |
| Asp 1033 | - | expression tag |
| Glu 1034 | - | expression tag |
| Val 1035 | - | expression tag |
| Asp 1036 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 177868.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1769.7 | |
| All* | Total formula weight | 179638.2 |
