7NX3
Crystal structure of ALK in complex with Fab324
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, F | ALK tyrosine kinase receptor | polymer | 389 | 40499.7 | 2 | UniProt (Q9UM73) Pfam (PF12810) In PDB | Homo sapiens (Human) | Anaplastic lymphoma kinase |
2 | B, E | Fab324 HeavyChain | polymer | 231 | 24516.2 | 2 | Mus musculus | ||
3 | C, D | Fab324 Light Chain | polymer | 218 | 23918.4 | 2 | Mus musculus | ||
4 | A, F | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 8 | Chemie (NAG) |
Sequence modifications
A, F: 648 - 1030 (UniProt: Q9UM73)
PDB | External Database | Details |
---|---|---|
Gly 1031 | - | expression tag |
Thr 1032 | - | expression tag |
Asp 1033 | - | expression tag |
Glu 1034 | - | expression tag |
Val 1035 | - | expression tag |
Asp 1036 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 177868.6 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1769.7 | |
All* | Total formula weight | 179638.2 |