7NPI
Crystal structure of Mindy2 (C266A) in complex with Lys48-linked penta-ubiquitin (K48-Ub5)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, EA, G, KA, M... (A, G, M, S, Y...) | Ubiquitin carboxyl-terminal hydrolase MINDY-2 | polymer | 273 | 31168.4 | 7 | UniProt (Q8NBR6) Pfam (PF04424) | Homo sapiens (Human) | Deubiquitinating enzyme MINDY-2,Protein FAM63B |
| 2 | AA, B, BA, C, CA... (B, C, D, E, F...) | Polyubiquitin-C | polymer | 76 | 8576.8 | 35 | UniProt (P0CG48) Pfam (PF00240) | Homo sapiens (Human) | |
| 3 | QA, RA (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | SA, TA (A, S) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | AB, BB, CB, UA, VA... (Z, e, m, A, E...) | water | water | 18.0 | 16 | Chemie (HOH) |
Sequence modifications
A, G, M, S, Y, e, k: 241 - 504 (UniProt: Q8NBR6)
| PDB | External Database | Details |
|---|---|---|
| Gly 232 | - | expression tag |
| Pro 233 | - | expression tag |
| Leu 234 | - | expression tag |
| Gly 235 | - | expression tag |
| Ser 236 | - | expression tag |
| Pro 237 | - | expression tag |
| Glu 238 | - | expression tag |
| Phe 239 | - | expression tag |
| Met 240 | - | expression tag |
| Ala 266 | Cys 266 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 42 |
| Total formula weight | 518367.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 116.9 | |
| All* | Total formula weight | 518484.7 |
