7N3P

Cryo-EM structure of the Cas12k-sgRNA-dsDNA complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Cas12k	polymer	639	73280.7	1	UniProt (by SIFTS) (A0A8M0FGU0)	Scytonema hofmannii
2	B (B)	Single guide RNA	polymer	265	85261.3	1		Scytonema hofmannii
3	C (C)	DNA (5'-D(*CP*AP*TP*GP*AP*CP*TP*TP*CP*TP*CP*AP*AP*CP*CP*GP*AP*GP*TP*TP*T)-3')	polymer	40	12181.9	1		Scytonema hofmannii
4	D (D)	DNA (5'-D(P*AP*AP*AP*CP*TP*CP*GP*GP*TP*T)-3')	polymer	11	3429.2	1		Scytonema hofmannii

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	174153.1
All*	Total formula weight	174153.1

*Water molecules are not included.