7N0A
Structure of Human Leukaemia Inhibitory Factor with Fab MSC1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | Leukemia inhibitory factor | polymer | 181 | 19796.9 | 1 | UniProt (P15018) Pfam (PF01291) | Homo sapiens (Human) | LIF,Differentiation-stimulating factor,D factor,Melanoma-derived LPL inhibitor,MLPLI |
| 2 | B (A) | MSC-1 Fab Light chain | polymer | 220 | 24033.7 | 1 | Homo sapiens (Human) | ||
| 3 | C (B) | MSC-1 Fab Heavy chain | polymer | 224 | 24145.1 | 1 | Homo sapiens (Human) | ||
| 4 | D (E) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 5 | E, F, G (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 6 | H (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 7 | I, J, K (C, A, B) | water | water | 18.0 | 7 | Chemie (HOH) |
Sequence modifications
C: 1 - 180 (UniProt: P15018)
| PDB | External Database | Details |
|---|---|---|
| Gly 181 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 67975.7 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 586.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 755.7 | |
| All* | Total formula weight | 69318.0 |
