7MSG
The crystal structure of LIGHT in complex with HVEM and CD160
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Tumor necrosis factor ligand superfamily member 14, membrane form | polymer | 165 | 18188.5 | 3 | UniProt (O43557) Pfam (PF00229) In PDB | Homo sapiens (Human) | |
| 2 | D, E, F | CD160 antigen, soluble form,Tumor necrosis factor receptor superfamily member 14 | polymer | 250 | 26314.7 | 3 | UniProt (O95971) UniProt (Q92956) Pfam (PF00020) In PDB | Homo sapiens (Human) | Herpes virus entry mediator A,Tumor necrosis factor receptor-like 2 |
| 3 | H, J, L | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 4 | I, K, M | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) |
Sequence modifications
A, B, C: 83 - 240 (UniProt: O43557)
D, E, F: 27 - 1018 (UniProt: O95971)
D, E, F: 1039 - 1143 (UniProt: Q92956)
| PDB | External Database | Details |
|---|---|---|
| His 76 | - | expression tag |
| His 77 | - | expression tag |
| His 78 | - | expression tag |
| His 79 | - | expression tag |
| His 80 | - | expression tag |
| His 81 | - | expression tag |
| Gly 82 | - | expression tag |
| Glu 214 | Lys 214 | variant |
| PDB | External Database | Details |
|---|---|---|
| Gly 1019 | - | linker |
| Gly 1020 | - | linker |
| Gly 1021 | - | linker |
| Gly 1022 | - | linker |
| Ser 1023 | - | linker |
| Gly 1024 | - | linker |
| Gly 1025 | - | linker |
| Gly 1026 | - | linker |
| Gly 1027 | - | linker |
| Ser 1028 | - | linker |
| Gly 1029 | - | linker |
| Gly 1030 | - | linker |
| Gly 1031 | - | linker |
| Gly 1032 | - | linker |
| Ser 1033 | - | linker |
| Gly 1034 | - | linker |
| Gly 1035 | - | linker |
| Gly 1036 | - | linker |
| Gly 1037 | - | linker |
| Ser 1038 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Gly 1144 | - | expression tag |
| His 1145 | - | expression tag |
| His 1146 | - | expression tag |
| His 1147 | - | expression tag |
| His 1148 | - | expression tag |
| His 1149 | - | expression tag |
| His 1150 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 133509.7 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 3032.8 | |
| All* | Total formula weight | 136542.5 |
