7MS5
Structure of USP5 zinc-finger ubiquitin binding domain co-crystallized with 4-(4-(4-(3,4-difluoro-phenyl)-piperidin-1-ylsulfonyl)-phenyl)-4-oxo-butanoic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Ubiquitin carboxyl-terminal hydrolase 5 | polymer | 121 | 13535.2 | 2 | UniProt (P45974) Pfam (PF02148) In PDB | Homo sapiens (Human) | Deubiquitinating enzyme 5, Isopeptidase T, Ubiquitin thioesterase 5, Ubiquitin-specific-processing protease 5 |
| 2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | A, B | 4-{4-[4-(3,4-difluorophenyl)piperidine-1-sulfonyl]phenyl}-4-oxobutanoic acid | non-polymer | 437.5 | 2 | Chemie (ZOG) | |||
| 4 | B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | B | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 6 | water | water | 18.0 | 214 | Chemie (HOH) |
Sequence modifications
A, B: 171 - 290 (UniProt: P45974)
| PDB | External Database | Details |
|---|---|---|
| Gly 170 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27070.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1107.9 | |
| All* | Total formula weight | 28178.3 |
