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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

7MQ9

Cryo-EM structure of the human SSU processome, state pre-A1*

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1L05'ETS rRNApolymer36171166881.91GenBank (1212788588)Homo sapiens
2L118S rRNApolymer1872603757.51GenBank (151415227)Homo sapiens
3L2U3 snoRNApolymer21770017.21GenBank (37551)Homo sapiens
4L340S ribosomal protein S18polymer11612672.01Homo sapiens (Human)
5L440S ribosomal protein S4 X isoformpolymer26329654.91Homo sapiens (Human)
6L540S ribosomal protein S5polymer20422913.51UniProt (P46782)
Pfam (PF00177)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS7
7L640S ribosomal protein S6polymer24928751.91UniProt (P62753)
Pfam (PF01092)
In PDB		Homo sapiens (Human)Phosphoprotein NP33,Small ribosomal subunit protein eS6
8L740S ribosomal protein S7polymer19422168.91UniProt (P62081)
Pfam (PF01251)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS7
9L840S ribosomal protein S8polymer20824263.41UniProt (P62241)
Pfam (PF01201)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS8
10L940S ribosomal protein S9polymer19422641.61UniProt (P46781)
Pfam (PF00163)
Pfam (PF01479)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS4
11LA40S ribosomal protein S12polymer13214539.01UniProt (P25398)
Pfam (PF01248)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS12
12LC40S ribosomal protein S16polymer14616477.41UniProt (P62249)
Pfam (PF00380)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS9
13LD40S ribosomal protein S11polymer15818468.81UniProt (P62280)
Pfam (PF00366)
Pfam (PF16205)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS17
14LF40S ribosomal protein S24polymer13315463.31UniProt (P62847)
Pfam (PF01282)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS24
15LG40S ribosomal protein S28polymer697855.11UniProt (P62857)
Pfam (PF01200)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS28
16LHWD repeat-containing protein 75polymer83094609.61UniProt (Q8IWA0)
Pfam (PF00400)
In PDB		Homo sapiens (Human)U3 small nucleolar RNA-associated protein 17 homolog
17LINucleolar protein 11polymer69975231.91Homo sapiens (Human)
18LJU3 small nucleolar RNA-associated protein 15 homologpolymer51858503.21UniProt (Q8TED0)
Pfam (PF00400)
Pfam (PF09384)
In PDB		Homo sapiens (Human)
19LK, LLWD repeat-containing protein 43polymer67774985.62UniProt (Q15061)
Pfam (PF00400)
Pfam (PF04003)
In PDB		Homo sapiens (Human)U3 small nucleolar RNA-associated protein 5 homolog
20LNU3 small nucleolar RNA-associated protein 4 homologpolymer68676993.11UniProt (Q969X6)
Pfam (PF00400)
In PDB		Homo sapiens (Human)Cirhin,UTP4 small subunit processome component
21LOPeriodic tryptophan protein 2 homologpolymer919102575.01UniProt (Q15269)
Pfam (PF00400)
Pfam (PF04003)
In PDB		Homo sapiens (Human)
22LPU3 small nucleolar RNA-associated protein 6 homologpolymer59770297.91UniProt (Q9NYH9)
Pfam (PF08640)
In PDB		Homo sapiens (Human)Hepatocellular carcinoma-associated antigen 66,Multiple hat domains protein
23LQWD repeat-containing protein 3polymer943106248.01UniProt (Q9UNX4)
Pfam (PF12894)
Pfam (PF00400)
Pfam (PF04003)
In PDB		Homo sapiens (Human)
24LSU3 small nucleolar RNA-associated protein 18 homologpolymer55662097.51UniProt (Q9Y5J1)
Pfam (PF00400)
In PDB		Homo sapiens (Human)WD repeat-containing protein 50
25LTWD repeat-containing protein 36polymer951105443.01UniProt (Q8NI36)
Pfam (PF00400)
Pfam (PF12894)
Pfam (PF04192)
In PDB		Homo sapiens (Human)T-cell activation WD repeat-containing protein,TA-WDRP
26LUDDB1- and CUL4-associated factor 13polymer44551489.31UniProt (Q9NV06)
Pfam (PF00400)
Pfam (PF08662)
Pfam (PF04158)
In PDB		Homo sapiens (Human)WD repeat and SOF domain-containing protein 1
27LWWD repeat-containing protein 46polymer61068189.21UniProt (O15213)
Pfam (PF00400)
Pfam (PF08149)
In PDB		Homo sapiens (Human)WD repeat-containing protein BING4
28LZU3 small nucleolar ribonucleoprotein protein IMP3polymer18421889.21UniProt (Q9NV31)
Pfam (PF00163)
Pfam (PF01479)
In PDB		Homo sapiens (Human)U3 snoRNP protein IMP3,BRMS2
29NAU3 small nucleolar ribonucleoprotein protein MPP10polymer68178988.81UniProt (O00566)
Pfam (PF04006)
In PDB		Homo sapiens (Human)M phase phosphoprotein 10
30NBSomething about silencing protein 10polymer47954652.01UniProt (Q9NQZ2)
Pfam (PF04000)
Pfam (PF09368)
In PDB		Homo sapiens (Human)Charged amino acid-rich leucine zipper 1,CRL1,Disrupter of silencing SAS10,UTP3 homolog
31NDNucleolar protein 7polymer25729483.51UniProt (Q9UMY1)
Pfam (PF08157)
In PDB		Homo sapiens (Human)Nucleolar protein of 27 kDa
32NEUncharacterized protein C1orf131polymer29332673.41UniProt (Q8NDD1)
Pfam (PF15375)
In PDB		Homo sapiens (Human)
33NF40S ribosomal protein S13polymer15117259.41UniProt (P62277)
Pfam (PF08069)
Pfam (PF00312)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS15
34NG40S ribosomal protein S14polymer15116302.81UniProt (P62263)
Pfam (PF00411)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS11
35NJ, NKRNA cytidine acetyltransferasepolymer1025115882.82UniProt (Q9H0A0)
Pfam (PF08351)
Pfam (PF05127)
Pfam (PF13718)
Pfam (PF13725)
In PDB		Homo sapiens (Human)18S rRNA cytosine acetyltransferase,N-acetyltransferase 10,N-acetyltransferase-like protein,hALP
36NM40S ribosomal protein S3apolymer26430002.11UniProt (P61247)
Pfam (PF01015)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS1,v-fos transformation effector protein,Fte-1
37NNProtein AATFpolymer56063224.91UniProt (Q9NY61)
Pfam (PF13339)
Pfam (PF08164)
In PDB		Homo sapiens (Human)Apoptosis-antagonizing transcription factor,Rb-binding protein Che-1
38NO40S ribosomal protein S15apolymer13014865.61UniProt (P62244)
Pfam (PF00410)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS8
39NQ40S ribosomal protein S27polymer849480.21UniProt (P42677)
Pfam (PF01667)
In PDB		Homo sapiens (Human)Metallopan-stimulin 1,MPS-1,Small ribosomal subunit protein eS27
40NRRRP12-like proteinpolymer86173292.81Homo sapiens (Human)
41NTUbiquitin-40S ribosomal protein S27apolymer15618004.01UniProt (P62979)
Pfam (PF00240)
Pfam (PF01599)
In PDB		Homo sapiens (Human)Ubiquitin carboxyl extension protein 80
42NU40S ribosomal protein S17polymer13515578.21UniProt (P08708)
Pfam (PF00833)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS17
43NWNucleolar protein 10polymer68880431.61UniProt (Q9BSC4)
Pfam (PF08159)
In PDB		Homo sapiens (Human)
44SANucleolar protein 56polymer59466160.11UniProt (O00567)
Pfam (PF08156)
Pfam (PF01798)
In PDB		Homo sapiens (Human)Nucleolar protein 5A
45SBNucleolar protein 58polymer52959686.31UniProt (Q9Y2X3)
Pfam (PF08156)
Pfam (PF01798)
In PDB		Homo sapiens (Human)Nucleolar protein 5
46SC, SDrRNA 2'-O-methyltransferase fibrillarinpolymer32133843.32UniProt (P22087)
Pfam (PF01269)
In PDB		Homo sapiens (Human)34 kDa nucleolar scleroderma antigen,Histone-glutamine methyltransferase,U6 snRNA 2'-O-methyltransferase fibrillarin
47SE, SFNHP2-like protein 1polymer12814191.52UniProt (P55769)
Pfam (PF01248)
In PDB		Homo sapiens (Human)High mobility group-like nuclear protein 2 homolog 1,OTK27,SNU13 homolog,hSNU13,U4/U6.U5 small nuclear ribonucleoprotein SNU13,U4/U6.U5 tri-snRNP 15.5 kDa protein
48SHRNA 3'-terminal phosphate cyclase-like proteinpolymer37340893.61UniProt (Q9Y2P8)
Pfam (PF01137)
Pfam (PF05189)
In PDB		Homo sapiens (Human)
49SIRibosome biogenesis protein BMS1 homologpolymer1282146045.01UniProt (Q14692)
Pfam (PF08142)
Pfam (PF04950)
In PDB		Homo sapiens (Human)Ribosome assembly protein BMS1 homolog
50SK, SJRibosomal RNA small subunit methyltransferase NEP1polymer24426757.12UniProt (Q92979)
Pfam (PF03587)
In PDB		Homo sapiens (Human)18S rRNA (pseudouridine(1248)-N1)-methyltransferase,18S rRNA Psi1248 methyltransferase,Nucleolar protein EMG1 homolog,Protein C2f,Ribosome biogenesis protein NEP1
51SLrRNA-processing protein FCF1 homologpolymer19823416.71UniProt (Q9Y324)
Pfam (PF04900)
In PDB		Homo sapiens (Human)
52SMU3 small nucleolar ribonucleoprotein protein IMP4polymer29133818.71UniProt (Q96G21)
Pfam (PF04427)
In PDB		Homo sapiens (Human)U3 snoRNP protein IMP4,Brix domain-containing protein 4
53SQDeoxynucleotidyltransferase terminal-interacting protein 2polymer75684598.11UniProt (Q5QJE6)
Pfam (PF08698)
In PDB		Homo sapiens (Human)Estrogen receptor-binding protein,LPTS-interacting protein 2,LPTS-RP2,Terminal deoxynucleotidyltransferase-interacting factor 2,TdIF2,TdT-interacting factor 2
54SR40S ribosomal protein S23polymer14315844.71UniProt (P62266)
Pfam (PF00164)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS12
55SSU3 small nucleolar RNA-associated protein 14 homolog Apolymer77188129.11UniProt (Q9BVJ6)
Pfam (PF04615)
In PDB		Homo sapiens (Human)Antigen NY-CO-16,Serologically defined colon cancer antigen 16
56SXUnassigned peptidespolymer17715081.61Homo sapiens (Human)
57SYProbable U3 small nucleolar RNA-associated protein 11polymer25330520.81UniProt (Q9Y3A2)
Pfam (PF03998)
In PDB		Homo sapiens (Human)U3 snoRNA-associated protein 11,UTP11-like protein
58NHNucleolar protein 6polymer1146127748.61UniProt (Q9H6R4)
Pfam (PF03813)
Pfam (PF17403)
Pfam (PF17404)
Pfam (PF17405)
Pfam (PF17406)
Pfam (PF17407)
In PDB		Homo sapiens (Human)Nucleolar RNA-associated protein,Nrap
59SPSmall subunit processome component 20 homologpolymer2785318813.31UniProt (O75691)
Pfam (PF07539)
Pfam (PF20416)
In PDB		Homo sapiens (Human)Down-regulated in metastasis protein,Novel nucleolar protein 73,NNP73,Protein Key-1A6
60LRTransducin beta-like protein 3polymer80889143.61UniProt (Q12788)
Pfam (PF00400)
Pfam (PF08625)
In PDB		Homo sapiens (Human)WD repeat-containing protein SAZD
61LMHEAT repeat-containing protein 1polymer2144242649.71UniProt (Q9H583)
Pfam (PF12397)
Pfam (PF08146)
In PDB		Homo sapiens (Human)Protein BAP28,U3 small nucleolar RNA-associated protein 10 homolog
62N05' ETS rRNApolymer227197.61Homo sapiens (Human)
63SGU3 small nucleolar RNA-interacting protein 2polymer47551920.71UniProt (O43818)
Pfam (PF00400)
In PDB		Homo sapiens (Human)RRP9 homolog,U3 small nucleolar ribonucleoprotein-associated 55 kDa protein,U3 snoRNP-associated 55 kDa protein,U3-55K
64NIRibosomal RNA-processing protein 7 homolog Apolymer28032393.21UniProt (Q9Y3A4)
Pfam (PF17799)
Pfam (PF12923)
In PDB		Homo sapiens (Human)Gastric cancer antigen Zg14
65SWRNA-binding protein PNO1polymer25227970.41UniProt (Q9NRX1)
In PDB		Homo sapiens (Human)Partner of NOB1
66STNucleolar protein 14polymer63268259.51Homo sapiens (Human)
67SUNucleolar complex protein 4 homologpolymer47250184.11Homo sapiens (Human)
68NYKRR1 small subunit processome component homologpolymer38143751.11UniProt (Q13601)
Pfam (PF17903)
Pfam (PF21800)
In PDB		Homo sapiens (Human)HIV-1 Rev-binding protein 2,KRR-R motif-containing protein 1,Rev-interacting protein 1,Rip-1
69SZBystinpolymer30433712.91Homo sapiens (Human)
70L1, SI, SL, NHMAGNESIUM IONnon-polymer24.322Chemie (MG)
71NQ, NT, SLZINC IONnon-polymer65.43Chemie (ZN)
72SIGUANOSINE-5'-TRIPHOSPHATEnon-polymer523.21Chemie (GTP)
73SK, SJS-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.42Chemie (SAH)
74NH, NKADENOSINE-5'-TRIPHOSPHATEnon-polymer507.22Chemie (ATP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains74
Total formula weight5733592.1
Non-Polymers*Number of molecules30
Total formula weight3037.3
All*Total formula weight5736629.4
*Water molecules are not included.

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PDB entries from 2024-06-12

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