7MNW
Crystal Structure of Nup358/RanBP2 Ran-binding domain 1 in complex with Ran-GPPNHP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G | GTP-binding nuclear protein Ran | polymer | 217 | 24543.2 | 4 | UniProt (P62826) Pfam (PF00071) In PDB | Homo sapiens (Human) | Androgen receptor-associated protein 24,GTPase Ran,Ras-like protein TC4,Ras-related nuclear protein |
| 2 | B, D, F, H | E3 SUMO-protein ligase RanBP2 | polymer | 140 | 16243.7 | 4 | UniProt (P49792) Pfam (PF00638) In PDB | Homo sapiens (Human) | 358 kDa nucleoporin,Nuclear pore complex protein Nup358,Nucleoporin Nup358,Ran-binding protein 2,RanBP2,p270 |
| 3 | A, C, E, G | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 4 | Chemie (GNP) | |||
| 4 | A, C, E, G | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 5 | water | water | 18.0 | 402 | Chemie (HOH) |
Sequence modifications
A, C, E, G: 1 - 216 (UniProt: P62826)
B, D, F, H: 1171 - 1306 (UniProt: P49792)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 1167 | - | expression tag |
| Pro 1168 | - | expression tag |
| Gly 1169 | - | expression tag |
| Ser 1170 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 163147.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2186.0 | |
| All* | Total formula weight | 165333.4 |
