7MKC
N74D mutant of the HIV-1 capsid protein in complex with PF-3450074 (PF74)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | capsid protein | polymer | 231 | 25631.4 | 1 | UniProt (B6DRA0) Pfam (PF00607) Pfam (PF19317) UniProt (by SIFTS) (P12493) | Human immunodeficiency virus 1 | Gag polyprotein |
| 2 | B (A) | N-METHYL-NALPHA-[(2-METHYL-1H-INDOL-3-YL)ACETYL]-N-PHENYL-L-PHENYLALANINAMIDE | non-polymer | 425.5 | 1 | Chemie (1B0) | |||
| 3 | C, D, E, F, G... (A) | IODIDE ION | non-polymer | 126.9 | 6 | Chemie (IOD) | |||
| 4 | I (A) | water | water | 18.0 | 16 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: B6DRA0)
| PDB | External Database | Details |
|---|---|---|
| Asp 74 | Asn 206 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 25631.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1186.9 | |
| All* | Total formula weight | 26818.4 |
