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7MKC

N74D mutant of the HIV-1 capsid protein in complex with PF-3450074 (PF74)

Functional Information from GO Data
ChainGOidnamespacecontents
A0016032biological_processviral process
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI2
Number of Residues38
DetailsRegion: {"description":"Interaction with human PPIA/CYPA and NUP153","evidences":[{"source":"PubMed","id":"24130490","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8980234","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues8
DetailsRegion: {"description":"PPIA/CYPA-binding loop","evidences":[{"source":"UniProtKB","id":"P04591","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues1
DetailsModified residue: {"description":"Phosphoserine; by host MAPK1","evidences":[{"source":"PubMed","id":"24509437","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

240971

PDB entries from 2025-08-27

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