7M8V
Human CYP11B2 in complex with LCI699
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | Cytochrome P450 11B2, mitochondrial | polymer | 484 | 55698.6 | 12 | UniProt (P19099) Pfam (PF00067) In PDB | Homo sapiens (Human) | Aldosterone synthase,ALDOS,Aldosterone-synthesizing enzyme,CYPXIB2,Corticosterone 18-monooxygenase,CYP11B2,Cytochrome P-450Aldo,Cytochrome P-450C18,Steroid 11-beta-hydroxylase,Steroid 18-hydroxylase |
| 2 | H, I, J, K, L... | 4-[(4R,5R)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl]-3-fluorobenzonitrile | non-polymer | 227.2 | 12 | Chemie (YSY) | |||
| 3 | H, I, J, K, L... | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 12 | Chemie (HEM) | |||
| 4 | water | water | 18.0 | 6 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 31 - 503 (UniProt: P19099)
| PDB | External Database | Details |
|---|---|---|
| Met 24 | - | initiating methionine |
| Ala 25 | - | expression tag |
| Lys 26 | - | expression tag |
| Lys 27 | - | expression tag |
| Thr 28 | - | expression tag |
| Ser 29 | - | expression tag |
| Ser 30 | - | expression tag |
| His 504 | - | expression tag |
| His 505 | - | expression tag |
| His 506 | - | expression tag |
| His 507 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 668383.2 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 10124.7 | |
| All* | Total formula weight | 678507.9 |
