7M66
Targeting Enterococcus faecalis HMG-CoA reductase with a novel non-statin inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Hydroxymethylglutaryl-CoA reductase, degradative | polymer | 423 | 46105.6 | 4 | UniProt (A0A4U3MLJ4) | Enterococcus faecalis (Streptococcus faecalis) | |
| 2 | E, T (A, C) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | AA, F, M, N, Z (D, A, B) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 5 | Chemie (MES) | |||
| 4 | BA, G, H, I, V... (D, A, C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 6 | Chemie (PEG) | |||
| 5 | CA, DA, EA, J, K... (D, A, B, C) | CALCIUM ION | non-polymer | 40.1 | 10 | Chemie (CA) | |||
| 6 | O, P, Q, U (B, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 7 | FA, GA, HA, IA (A, B, C, D) | water | water | 18.0 | 646 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 184422.2 | |
| Non-Polymers* | Number of molecules | 27 |
| Total formula weight | 2454.1 | |
| All* | Total formula weight | 186876.3 |
