7M66

Targeting Enterococcus faecalis HMG-CoA reductase with a novel non-statin inhibitor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004420	molecular_function	hydroxymethylglutaryl-CoA reductase (NADPH) activity
A	0015936	biological_process	coenzyme A metabolic process
A	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
B	0004420	molecular_function	hydroxymethylglutaryl-CoA reductase (NADPH) activity
B	0015936	biological_process	coenzyme A metabolic process
B	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
C	0004420	molecular_function	hydroxymethylglutaryl-CoA reductase (NADPH) activity
C	0015936	biological_process	coenzyme A metabolic process
C	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
D	0004420	molecular_function	hydroxymethylglutaryl-CoA reductase (NADPH) activity
D	0015936	biological_process	coenzyme A metabolic process
D	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

Functional Information from PROSITE/UniProt

site_id	PS01192
Number of Residues	14
Details	HMG_COA_REDUCTASE_3 Hydroxymethylglutaryl-coenzyme A reductases signature 3. ALvSegIqKGHMaL

Chain	Residue	Details
A	ALA366-LEU379

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