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7M65

Cryo-EM structure of human islet amyloid polypeptide (hIAPP, or amylin) fibrils seeded by patient extracted fibrils, polymorph 4

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...Islet amyloid polypeptidepolymer383907.310UniProt (P10997)
Pfam (PF00214)
In PDB
Homo sapiensAmylin,Diabetes-associated peptide,DAP,Insulinoma amyloid peptide
Sequence modifications
A, B, C, D, E, F, G, H, I, J: 1 - 37 (UniProt: P10997)
PDBExternal DatabaseDetails
Nh2 38-amidation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains10
Total formula weight39073.1
All*Total formula weight39073.1
*Water molecules are not included.

222624

PDB entries from 2024-07-17

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