7M22
Cryo-EM structure of the HCMV pentamer bound by human neuropilin 2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | C | Envelope protein UL128 | polymer | 144 | 16684.3 | 1 | UniProt (C8BLJ3) UniProt (by SIFTS) (P16837) In PDB | Human cytomegalovirus (HHV-5) | UL128 |
2 | D | Envelope glycoprotein UL130 | polymer | 189 | 21761.7 | 1 | UniProt (A0A0G2TB82) Pfam (PF11668) UniProt (by SIFTS) (P16772) In PDB | Human cytomegalovirus (HHV-5) | ORFL272C_UL130,UL130 protein |
3 | E | UL131A | polymer | 111 | 13005.5 | 1 | UniProt (Q38M21) UniProt (by SIFTS) (F5HET4) In PDB | Human cytomegalovirus (HHV-5) | |
4 | N | Neuropilin-2 | polymer | 581 | 65430.4 | 1 | UniProt (O60462) Pfam (PF00431) Pfam (PF00754) In PDB | Homo sapiens (Human) | Vascular endothelial cell growth factor 165 receptor 2 |
5 | E, N | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
6 | N | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) |
Sequence modifications
N: 23 - 595 (UniProt: O60462)
PDB | External Database | Details |
---|---|---|
Gly 596 | - | expression tag |
Ser 597 | - | expression tag |
Leu 598 | - | expression tag |
Glu 599 | - | expression tag |
Val 600 | - | expression tag |
Leu 601 | - | expression tag |
Phe 602 | - | expression tag |
Gln 603 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 116881.9 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 482.5 | |
All* | Total formula weight | 117364.4 |