7M22

Cryo-EM structure of the HCMV pentamer bound by human neuropilin 2

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0019031	cellular_component	viral envelope
E	0019062	biological_process	virion attachment to host cell
E	0044423	cellular_component	virion component
E	0046718	biological_process	symbiont entry into host cell
E	0055036	cellular_component	virion membrane
E	0098670	biological_process	entry receptor-mediated virion attachment to host cell

Functional Information from PROSITE/UniProt

site_id	PS01285
Number of Residues	30
Details	FA58C_1 Coagulation factors 5/8 type C domain (FA58C) signature 1. GWtpnldsnke......YLqVDlrfltmLtaIaTQG

Chain	Residue	Details
N	GLY317-GLY346
N	GLY473-GLY505

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site_id	PS01286
Number of Residues	17
Details	FA58C_2 Coagulation factors 5/8 type C domain (FA58C) signature 2. Pqtwhsgia..LRlELfGC

Chain	Residue	Details
N	PRO411-CYS427
N	PRO575-CYS592

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	150
Details	Domain: {"description":"F5/8 type C 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00081","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	19
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	12
Details	Compositional bias: {"description":"Polar residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17989695","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2QQO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"17989695","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2QQK","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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