7M0L
HPK1 IN COMPLEX WITH COMPOUND 1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Mitogen-activated protein kinase kinase kinase kinase 1 | polymer | 290 | 32587.9 | 4 | UniProt (Q92918) Pfam (PF00069) In PDB | Homo sapiens (Human) | Hematopoietic progenitor kinase,MAPK/ERK kinase kinase kinase 1,MEK kinase kinase 1,MEKKK 1 |
2 | A, B, C, D | 4-(2-bromoanilino)-2-[(6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino]pyrimidine-5-carboxamide | non-polymer | 483.4 | 4 | Chemie (YK4) | |||
3 | water | water | 18.0 | 72 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 5 - 294 (UniProt: Q92918)
PDB | External Database | Details |
---|---|---|
Glu 165 | Thr 165 | conflict |
Glu 171 | Ser 171 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 130351.4 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1933.4 | |
All* | Total formula weight | 132284.9 |