7LW9
Human Exonuclease 5 crystal structure in complex with ssDNA, Sm, and Na
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Exonuclease V | polymer | 346 | 38856.9 | 1 | UniProt (Q9H790) Pfam (PF09810) | Homo sapiens (Human) | Exo V, hExo5, Defects in morphology protein 1 homolog |
| 2 | B (B) | DNA (5'-D(*AP*TP*TP*GP*CP*TP*GP*AP*AP*GP*GP*G)-3') | polymer | 12 | 3742.5 | 1 | synthetic construct | ||
| 3 | C (A) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 1 | Chemie (SF4) | |||
| 4 | D, E, K (A, B) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 5 | F, G (A) | SAMARIUM (III) ION | non-polymer | 150.4 | 2 | Chemie (SM) | |||
| 6 | H (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 7 | I, J (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 8 | L, M (A, B) | water | water | 18.0 | 30 | Chemie (HOH) |
Sequence modifications
A: 31 - 373 (UniProt: Q9H790)
| PDB | External Database | Details |
|---|---|---|
| Ser 28 | - | expression tag |
| Asn 29 | - | expression tag |
| Ala 30 | - | expression tag |
| Val 172 | Gly 172 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42599.4 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 976.6 | |
| All* | Total formula weight | 43576.0 |
