7LW9
Human Exonuclease 5 crystal structure in complex with ssDNA, Sm, and Na
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004518 | molecular_function | nuclease activity |
| A | 0004527 | molecular_function | exonuclease activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006281 | biological_process | DNA repair |
| A | 0006974 | biological_process | DNA damage response |
| A | 0008310 | molecular_function | single-stranded DNA 3'-5' DNA exonuclease activity |
| A | 0016607 | cellular_component | nuclear speck |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0036297 | biological_process | interstrand cross-link repair |
| A | 0045145 | molecular_function | single-stranded DNA 5'-3' DNA exonuclease activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"7LW7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LW8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LW9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LWA","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"7LWA","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"7LW7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LW8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LWA","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
