7LPS
Crystal structure of DDB1-CRBN-ALV1 complex bound to Helios (IKZF2 ZF2)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G, J (A, D, G, J) | DNA damage-binding protein 1 | polymer | 1140 | 127097.5 | 4 | UniProt (Q16531) Pfam (PF10433) Pfam (PF03178) | Homo sapiens (Human) | DDB p127 subunit,DNA damage-binding protein a,DDBa,Damage-specific DNA-binding protein 1,HBV X-associated protein 1,XAP-1,UV-damaged DNA-binding factor,UV-damaged DNA-binding protein 1,UV-DDB 1,XPE-binding factor,XPE-BF,Xeroderma pigmentosum group E-complementing protein,XPCe |
| 2 | B, E, H, K (B, E, H, K) | Protein cereblon | polymer | 390 | 44867.4 | 4 | UniProt (Q96SW2) Pfam (PF02190) Pfam (PF03226) | Homo sapiens (Human) | |
| 3 | C, F, I, L (C, F, I, L) | Zinc finger protein Helios | polymer | 29 | 3243.7 | 4 | UniProt (Q9UKS7) Pfam (PF00096) | Homo sapiens (Human) | Ikaros family zinc finger protein 2 |
| 4 | M, O, P, R, S... (B, C, E, F, H...) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 5 | N, Q, T, W (B, E, H, K) | 3-[3-[[1-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2,5-bis(oxidanylidene)pyrrol-3-yl]amino]phenyl]-~{N}-(3-chloranyl-4-methyl-phenyl)propanamide | non-polymer | 494.9 | 4 | Chemie (RN9) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 700834.3 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2503.0 | |
| All* | Total formula weight | 703337.3 |
