7LB4
Crystal structure of the second bromodomain (BD2) of human BRD3 bound to bromosporine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bromodomain-containing protein 3 | polymer | 113 | 13307.4 | 2 | UniProt (Q15059) Pfam (PF00439) | Homo sapiens (Human) | RING3-like protein |
| 2 | C, D (A, B) | Bromosporine | non-polymer | 404.4 | 2 | Chemie (BMF) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 131 | Chemie (HOH) |
Sequence modifications
A, B: 306 - 416 (UniProt: Q15059)
| PDB | External Database | Details |
|---|---|---|
| Ser 304 | - | expression tag |
| Met 305 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 26614.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 808.9 | |
| All* | Total formula weight | 27423.7 |
