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7LAH

Crystal structure of the first bromodomain (BD1) of human BRD2 bound to bromosporine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Bromodomain-containing protein 2polymer12214471.91UniProt (U3KQA6)
Pfam (PF00439)
Homo sapiens (Human)
2B
(A)
Bromosporinenon-polymer404.41Chemie (BMF)
3C
(A)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
4D
(A)
waterwater18.0113Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight14471.9
Non-Polymers*Number of molecules2
Total formula weight499.4
All*Total formula weight14971.3
*Water molecules are not included.

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PDB entries from 2024-11-13

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