7LAH
Crystal structure of the first bromodomain (BD1) of human BRD2 bound to bromosporine
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue BMF A 201 |
| Chain | Residue |
| A | TRP97 |
| A | ASN156 |
| A | ILE162 |
| A | LEU187 |
| A | HOH319 |
| A | HOH362 |
| A | PRO98 |
| A | GLN101 |
| A | PRO102 |
| A | VAL103 |
| A | ASP104 |
| A | LYS107 |
| A | LEU108 |
| A | TYR155 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | binding site for residue PO4 A 202 |
| Chain | Residue |
| A | PRO192 |
| A | PRO192 |
| A | LYS193 |
| A | LYS193 |
| A | HOH314 |
| A | HOH314 |
| A | HOH316 |
| A | HOH316 |
| A | HOH328 |
| A | HOH328 |
| A | HOH380 |
| A | HOH380 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 60 |
| Details | BROMODOMAIN_1 Bromodomain signature. AwpFrqpvDavklglpDYHkiIkqpMdmgtIkrrlenny..Ywaasecmqdfnt.MftNCyiY |
| Chain | Residue | Details |
| A | ALA96-TYR155 |
