7L73
Crystal structure of the first bromodomain (BD1) of human BRDT bound to ERK5-IN-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain testis-specific protein | polymer | 113 | 13319.4 | 1 | UniProt (Q58F21) Pfam (PF00439) | Homo sapiens (Human) | Cancer/testis antigen 9,CT9,RING3-like protein |
| 2 | B, C (A) | 11-cyclopentyl-2-({2-ethoxy-4-[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]phenyl}amino)-5-methyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one | non-polymer | 638.8 | 2 | Chemie (VYJ) | |||
| 3 | D (A) | water | water | 18.0 | 163 | Chemie (HOH) |
Sequence modifications
A: 29 - 137 (UniProt: Q58F21)
| PDB | External Database | Details |
|---|---|---|
| Gly 25 | - | expression tag |
| Ala 26 | - | expression tag |
| Ala 27 | - | expression tag |
| Ser 28 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13319.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1277.6 | |
| All* | Total formula weight | 14597.0 |
