7L2C
Crystallographic structure of neutralizing antibody 2-51 in complex with SARS-CoV-2 spike N-terminal domain (NTD)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Spike glycoprotein | polymer | 342 | 38862.0 | 2 | UniProt (P0DTC2) Pfam (PF16451) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | S glycoprotein,E2,Peplomer protein |
| 2 | H, C | 2-51 heavy chain | polymer | 227 | 24369.3 | 2 | Homo sapiens | ||
| 3 | L, D | 2-51 light chain | polymer | 215 | 22591.9 | 2 | Homo sapiens | ||
| 4 | E | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | B, A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 13 | Chemie (NAG) | |||
| 6 | C, B, D, H, A... | CALCIUM ION | non-polymer | 40.1 | 39 | Chemie (CA) | |||
| 7 | B, D, H, A, L | ACETATE ION | non-polymer | 59.0 | 9 | Chemie (ACT) | |||
| 8 | A | CACODYLATE ION | non-polymer | 137.0 | 1 | Chemie (CAC) | |||
| 9 | C | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 10 | water | water | 18.0 | 41 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 334 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Gly 335 | - | expression tag |
| Ser 336 | - | expression tag |
| Leu 337 | - | expression tag |
| Glu 338 | - | expression tag |
| Val 339 | - | expression tag |
| Leu 340 | - | expression tag |
| Phe 341 | - | expression tag |
| Gln 342 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 171646.4 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 63 |
| Total formula weight | 5257.3 | |
| All* | Total formula weight | 177328.1 |
