7KRZ

Human mitochondrial LONP1 in complex with Bortezomib

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Lon protease homolog, mitochondrial	polymer	534	59314.0	6	UniProt (P36776) Pfam (PF00004) Pfam (PF22667) Pfam (PF05362)	Homo sapiens (Human)	LONHs,Lon protease-like protein,LONP,Mitochondrial ATP-dependent protease Lon,Serine protease 15
2	G (G)	Endogenous co-purified substrate	polymer	12	1039.3	1		Escherichia coli BL21(DE3)
3	H, K, N, Q (A, B, C, D)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	4	Chemie (ATP)
4	I, L, O, R (A, B, C, D)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
5	J, M, P, S, U... (A, B, C, D, E...)	N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE	non-polymer		384.2	6	Chemie (BO2)
6	T, V (E, F)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	356923.4
Non-Polymers*	Number of molecules	16
	Total formula weight	5285.8
All*	Total formula weight	362209.1

*Water molecules are not included.