7KRZ
Human mitochondrial LONP1 in complex with Bortezomib
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Lon protease homolog, mitochondrial | polymer | 534 | 59314.0 | 6 | UniProt (P36776) Pfam (PF00004) Pfam (PF22667) Pfam (PF05362) In PDB | Homo sapiens (Human) | LONHs,Lon protease-like protein,LONP,Mitochondrial ATP-dependent protease Lon,Serine protease 15 |
2 | G | Endogenous co-purified substrate | polymer | 12 | 1039.3 | 1 | Escherichia coli BL21(DE3) | ||
3 | A, B, C, D | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 4 | Chemie (ATP) | |||
4 | A, B, C, D | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
5 | A, B, C, D, E... | N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE | non-polymer | 384.2 | 6 | Chemie (BO2) | |||
6 | E, F | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 7 |
Total formula weight | 356923.4 | |
Non-Polymers* | Number of molecules | 16 |
Total formula weight | 5285.8 | |
All* | Total formula weight | 362209.1 |