7KJM
CRYSTAL STRUCTURE OF HUMAN MDM2 IN COMPLEX WITH D-PEPTIDE INHIBITOR (DPMI-OMEGA)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | E3 ubiquitin-protein ligase Mdm2 | polymer | 85 | 10044.9 | 2 | UniProt (Q00987) Pfam (PF02201) | Homo sapiens | Double minute 2 protein,Hdm2,Oncoprotein Mdm2,RING-type E3 ubiquitin transferase Mdm2,p53-binding protein Mdm2 |
| 2 | B, D (B, D) | D-PMI-omega | polymer | 12 | 1694.3 | 2 | BIRD (PRD_002455) | synthetic construct | |
| 3 | E (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 4 | F (A) | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 1 | Chemie (IPA) | |||
| 5 | G, H (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 6 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 172 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 23478.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 237.1 | |
| All* | Total formula weight | 23715.6 |
