7KJM

CRYSTAL STRUCTURE OF HUMAN MDM2 IN COMPLEX WITH D-PEPTIDE INHIBITOR (DPMI-OMEGA)

Summary for 7KJM

• Entry DOI: 10.2210/pdb7kjm/pdb
• Related PRD ID: PRD_002455
• Descriptor: E3 ubiquitin-protein ligase Mdm2, D-PMI-omega, DI(HYDROXYETHYL)ETHER, ... (6 entities in total)
• Functional Keywords: mdm2, p53 binding domain, d-peptide activator of mdm2, mdm2-d-peptide complex, host-virus interaction, ligase, metal-binding, nucleus, phosphoprotein, proto-oncogene, ubl conjugation pathway, zinc-finger, ligase-ligase inhibitor complex, ligase/ligase inhibitor
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 23715.59

Authors

Tolbert, W.D.,Pazgier, M. (deposition date: 2020-10-26, release date: 2021-11-17, Last modification date: 2023-11-15)

• Primary citation: Tolbert, W.D.,Pazgier, M.; CRYSTAL STRUCTURE OF HUMAN MDM2 IN COMPLEX WITH D-PEPTIDE INHIBITOR (DPMI-OMEGA); To Be Published,

Experimental method

X-RAY DIFFRACTION (1.4 Å)