7KJC
Crystal structure of the EphA2 S901E mutant intracellular KD-SAM domains
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ephrin type-A receptor 2 | polymer | 390 | 44000.7 | 2 | UniProt (P29317) Pfam (PF07714) Pfam (PF00536) | Homo sapiens (Human) | Epithelial cell kinase,Tyrosine-protein kinase receptor ECK |
| 2 | C, H (A, B) | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | non-polymer | 505.2 | 2 | Chemie (ACP) | |||
| 3 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | E, F, G, I (A, B) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 5 | J, K (A, B) | water | water | 18.0 | 343 | Chemie (HOH) |
Sequence modifications
A, B: 590 - 976 (UniProt: P29317)
| PDB | External Database | Details |
|---|---|---|
| Gly 587 | - | expression tag |
| Pro 588 | - | expression tag |
| Gly 589 | - | expression tag |
| Glu 901 | Ser 901 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 88001.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1403.1 | |
| All* | Total formula weight | 89404.4 |
