7KHT
The acyl chains of phosphoinositide PIP3 alter the structure and function of nuclear receptor Steroidogenic Factor-1 (SF-1)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Steroidogenic factor 1 | polymer | 245 | 27903.4 | 1 | UniProt (Q13285) Pfam (PF00104) In PDB | Homo sapiens (Human) | hSF-1,Adrenal 4-binding protein,Fushi tarazu factor homolog 1,Nuclear receptor subfamily 5 group A member 1,Steroid hormone receptor Ad4BP |
| 2 | B | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha peptide | polymer | 14 | 1523.9 | 1 | UniProt (Q9UBK2) In PDB | Homo sapiens | PPARGC-1-alpha,Ligand effect modulator 6 |
| 3 | A | (2S)-3-{[(S)-{[(1S,2S,3R,4S,5S,6S)-2,6-dihydroxy-3,4,5-tris(phosphonooxy)cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}propane-1,2-diyl (9E,9'E)di-octadec-9-enoate | non-polymer | 1103.0 | 1 | Chemie (WES) | |||
| 4 | water | water | 18.0 | 33 | Chemie (HOH) |
Sequence modifications
A: 218 - 461 (UniProt: Q13285)
| PDB | External Database | Details |
|---|---|---|
| Gly 217 | - | expression tag |
| Ser 247 | Cys 247 | engineered mutation |
| Ser 412 | Cys 412 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29427.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 1103.0 | |
| All* | Total formula weight | 30530.3 |
