7KDO
Crystal structure of Escherichia coli HPPK in complex with bisubstrate inhibitor HP-73
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase | polymer | 158 | 17966.5 | 1 | UniProt (P26281) Pfam (PF01288) In PDB | Escherichia coli (strain K12) | 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase,PPPK,7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase,HPPK |
| 2 | A | 5'-S-[(2R,4R)-1-{2-[(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridine-6-carbonyl)amino]ethyl}-2-carboxypiperidin-4-yl]-5'-thioadenosine | non-polymer | 672.7 | 1 | Chemie (H73) | |||
| 3 | water | water | 18.0 | 170 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17966.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 672.7 | |
| All* | Total formula weight | 18639.3 |
