7JNI
Crystal structure of the angiotensin II type 2 receptoror (AT2R) in complex with EMA401
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Soluble cytochrome b562,Type-2 angiotensin II receptor | polymer | 412 | 46677.7 | 2 | UniProt (P0ABE7) UniProt (P50052) Pfam (PF07361) Pfam (PF00001) | Escherichia coli | Cytochrome b-562,Angiotensin II type-2 receptor,AT2 |
| 2 | C, L (A, B) | Olodanrigan | non-polymer | 507.6 | 2 | Chemie (VFD) | |||
| 3 | D, G, H (A) | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate | non-polymer | 356.5 | 3 | Chemie (OLC) | |||
| 4 | E, F, I, M (A, B) | OLEIC ACID | non-polymer | 282.5 | 4 | Chemie (OLA) | |||
| 5 | J (A) | FORMIC ACID | non-polymer | 46.0 | 1 | Chemie (FMT) | |||
| 6 | K (A) | HEXANE-1,6-DIOL | non-polymer | 118.2 | 1 | Chemie (HEZ) | |||
| 7 | N (A) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A, B: 1001 - 1106 (UniProt: P0ABE7)
A, B: 35 - 335 (UniProt: P50052)
| PDB | External Database | Details |
|---|---|---|
| Gly 1000 | - | expression tag |
| Trp 1007 | Met 29 | engineered mutation |
| Ile 1102 | His 124 | engineered mutation |
| Leu 1106 | Arg 128 | engineered mutation |
| Gly 900 | - | linker |
| Ser 901 | - | linker |
| Gly 902 | - | linker |
| Ser 903 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 93355.4 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 3378.8 | |
| All* | Total formula weight | 96734.2 |
