7JKL
Human PrimPol misinserting dATP opposite the 8-oxoguanine lesion (3'-end base of the primer strand is 2',3'-dideoxy-terminated).
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | DNA-directed primase/polymerase protein | polymer | 354 | 41038.5 | 2 | UniProt (Q96LW4) Pfam (PF01896) In PDB | Homo sapiens (Human) | hPrimpol1,Coiled-coil domain-containing protein 111 |
| 2 | C, G | DNA (5'-D(P*AP*(8OG)P*CP*GP*CP*TP*AP*CP*CP*AP*CP*AP*CP*CP*CP*C)-3') | polymer | 17 | 5078.3 | 2 | synthetic construct | ||
| 3 | D, H | DNA (5'-D(*GP*GP*GP*TP*GP*TP*GP*GP*TP*AP*GP*CP*(DDG))-3') | polymer | 13 | 4087.7 | 2 | synthetic construct | ||
| 4 | A, B | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE | non-polymer | 491.2 | 2 | Chemie (DTP) | |||
| 5 | A, B | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 6 | A, B | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 7 | water | water | 18.0 | 105 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 100408.9 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1286.8 | |
| All* | Total formula weight | 101695.7 |
