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7JKL

Human PrimPol misinserting dATP opposite the 8-oxoguanine lesion (3'-end base of the primer strand is 2',3'-dideoxy-terminated).

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, D
(A, B)
DNA-directed primase/polymerase proteinpolymer35441038.52UniProt (Q96LW4)
Pfam (PF01896)
Homo sapiens (Human)hPrimpol1,Coiled-coil domain-containing protein 111
2B, E
(C, G)
DNA (5'-D(P*AP*(8OG)P*CP*GP*CP*TP*AP*CP*CP*AP*CP*AP*CP*CP*CP*C)-3')polymer175078.32synthetic construct
3C, F
(D, H)
DNA (5'-D(*GP*GP*GP*TP*GP*TP*GP*GP*TP*AP*GP*CP*(DDG))-3')polymer134087.72synthetic construct
4G, L
(A, B)
2'-DEOXYADENOSINE 5'-TRIPHOSPHATEnon-polymer491.22Chemie (DTP)
5H, J, K
(A, B)
CALCIUM IONnon-polymer40.13Chemie (CA)
6I, M
(A, B)
GLYCEROLnon-polymer92.12Chemie (GOL)
7N, O, P, Q, R...
(A, C, D, B, G...)
waterwater18.0105Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight100408.9
Non-Polymers*Number of molecules7
Total formula weight1286.8
All*Total formula weight101695.7
*Water molecules are not included.

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PDB entries from 2025-12-10

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