7EXC

Crystal structure of T2R-TTL-1129A2 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Tubulin alpha-1B chain	polymer	451	50204.4	2	UniProt (Q2XVP4) Pfam (PF00091) Pfam (PF03953)	Sus scrofa (Pig)	Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain
2	B, D (B, D)	Tubulin beta chain	polymer	445	49907.8	2	UniProt (P02554) Pfam (PF00091) Pfam (PF03953)	Sus scrofa (Pig)	Beta-tubulin
3	E (E)	Stathmin-4	polymer	189	22125.3	1	UniProt (P63043) Pfam (PF00836)	Rattus norvegicus (Rat)	Stathmin-like protein B3,RB3
4	F (F)	Tubulin tyrosine ligase	polymer	384	44378.5	1	UniProt (E1BQ43)	Gallus gallus (Chicken)
5	G, O, R (A, C, D)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	3	Chemie (GTP)
6	H, K, P, T (A, B, C, D)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
7	I, Q (A, C)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
8	J (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
9	L (B)	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	1	Chemie (MES)
10	M, S (B, D)	N-[[3-(1,3-benzodioxol-5-yloxy)phenyl]methyl]-9H-pyrido[3,4-b]indol-3-amine	non-polymer		409.4	2	Chemie (JEL)
11	N (B)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	1	Chemie (GDP)
12	U (F)	PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER	non-polymer		505.2	1	Chemie (ACP)
13	AA, V, W, X, Y... (F, A, B, C, D...)	water	water		18.0	508	Chemie (HOH)

Sequence modifications

F: 1 - 378 (UniProt: E1BQ43)

PDB	External Database	Details
His 379	-	expression tag
His 380	-	expression tag
His 381	-	expression tag
His 382	-	expression tag
His 383	-	expression tag
His 384	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	266728.2
Non-Polymers*	Number of molecules	15
	Total formula weight	3801.5
All*	Total formula weight	270529.8

*Water molecules are not included.