7EX8
Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 27
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Replicase | polymer | 219 | 25181.9 | 1 | UniProt (A0A059WLS9) Pfam (PF15518) In PDB | Abbey lake orthobunyavirus | Transcriptase,L protein |
2 | A | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
3 | A | methyl (Z)-4-[1-[(3-chlorophenyl)methyl]-4-[(4-chlorophenyl)methyl]piperidin-4-yl]-2-oxidanyl-4-oxidanylidene-but-2-enoate | non-polymer | 462.4 | 1 | Chemie (I27) | |||
4 | A | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
5 | water | water | 18.0 | 82 | Chemie (HOH) |
Sequence modifications
A: 1 - 183 (UniProt: A0A059WLS9)
PDB | External Database | Details |
---|---|---|
Met -35 | - | initiating methionine |
Gly -34 | - | expression tag |
Ser -33 | - | expression tag |
Ser -32 | - | expression tag |
His -31 | - | expression tag |
His -30 | - | expression tag |
His -29 | - | expression tag |
His -28 | - | expression tag |
His -27 | - | expression tag |
His -26 | - | expression tag |
Ser -25 | - | expression tag |
Ser -24 | - | expression tag |
Gly -23 | - | expression tag |
Leu -22 | - | expression tag |
Val -21 | - | expression tag |
Pro -20 | - | expression tag |
Arg -19 | - | expression tag |
Gly -18 | - | expression tag |
Ser -17 | - | expression tag |
His -16 | - | expression tag |
Met -15 | - | expression tag |
Ala -14 | - | expression tag |
Ser -13 | - | expression tag |
Met -12 | - | expression tag |
Thr -11 | - | expression tag |
Gly -10 | - | expression tag |
Gly -9 | - | expression tag |
Gln -8 | - | expression tag |
Gln -7 | - | expression tag |
Met -6 | - | expression tag |
Gly -5 | - | expression tag |
Arg -4 | - | expression tag |
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
Glu -1 | - | expression tag |
Phe 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 25181.9 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 678.6 | |
All* | Total formula weight | 25860.5 |