7ENZ
Crystal structure of Phenanthredinone moiety in complex with the second bromodomain of BRD2 (BRD2-BD2).
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Bromodomain-containing protein 2 | polymer | 115 | 13406.3 | 1 | UniProt (P25440) Pfam (PF00439) In PDB | Homo sapiens (Human) | O27.1.1,Really interesting new gene 3 protein |
2 | A | phenanthridin-6(5H)-one | non-polymer | 195.2 | 1 | Chemie (LDR) | |||
3 | A | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
4 | water | water | 18.0 | 218 | Chemie (HOH) |
Sequence modifications
A: 348 - 455 (UniProt: P25440)
PDB | External Database | Details |
---|---|---|
Ala 341 | - | expression tag |
Ala 342 | - | expression tag |
His 343 | - | expression tag |
Gly 344 | - | expression tag |
Ser 345 | - | expression tag |
Asn 346 | - | expression tag |
Pro 347 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 13406.3 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 345.4 | |
All* | Total formula weight | 13751.7 |