7ENZ
Crystal structure of Phenanthredinone moiety in complex with the second bromodomain of BRD2 (BRD2-BD2).
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue LDR A 701 |
| Chain | Residue |
| A | PRO371 |
| A | VAL376 |
| A | ASN429 |
| A | HOH805 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue PGE A 702 |
| Chain | Residue |
| A | HOH862 |
| A | HOH886 |
| A | PRO347 |
| A | LEU350 |
| A | LYS351 |
| A | MET403 |
| A | HOH821 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 60 |
| Details | BROMODOMAIN_1 Bromodomain signature. AwpFykpvDasalglhDYHdiIkhpMdlstVkrkmenrd..Yrdaqefaadvrl.MfsNCykY |
| Chain | Residue | Details |
| A | ALA369-TYR428 |
