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7EHL

Cryo-EM structure of human ABCB8 transporter in nucleotide binding state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Mitochondrial potassium channel ATP-binding subunitpolymer67873628.42UniProt (Q9NUT2)
Pfam (PF00664)
Pfam (PF00005)
Homo sapiens (Human)ATP-binding cassette sub-family B member 8,mitochondrial,ABCB8,Mitochondrial ATP-binding cassette 1,M-ABC1,Mitochondrial sulfonylurea-receptor,MITOSUR
2C, E, G, H
(A, B)
CHOLESTEROLnon-polymer386.74Chemie (CLR)
3D, I
(A, B)
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERnon-polymer506.22Chemie (ANP)
4F, J
(A, B)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight147256.8
Non-Polymers*Number of molecules8
Total formula weight2607.6
All*Total formula weight149864.4
*Water molecules are not included.

247947

PDB entries from 2026-01-21

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