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7DW5

Crystal structure of DUX4 HD1-HD2 domain complexed with ERG sites

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Double homeobox protein 4-like protein 2polymer15017483.92UniProt (P0CJ85)
Pfam (PF00046)
Homo sapiens (Human)
2C, E
(E, C)
DNA (5'-D(P*CP*GP*AP*CP*TP*TP*GP*AP*TP*GP*AP*GP*AP*TP*TP*AP*GP*AP*CP*TP*G)-3')polymer216502.22Homo sapiens
3D, F
(F, D)
DNA (5'-D(P*CP*GP*AP*CP*TP*TP*GP*AP*TP*GP*AP*GP*AP*TP*TP*AP*GP*AP*CP*TP*G)-3')polymer216382.12Homo sapiens
4G
(E)
BROMIDE IONnon-polymer79.91Chemie (BR)
5H, I, J, K
(A, B, E, F)
waterwater18.08Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight60736.6
Non-Polymers*Number of molecules1
Total formula weight79.9
All*Total formula weight60816.5
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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