7DV4

Crystal structure of anti-CTLA-4 VH domain in complex with human CTLA-4

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G (A, C, E, G)	Cytotoxic T-lymphocyte protein 4	polymer	118	12669.5	4	UniProt (P16410) Pfam (PF07686)	Homo sapiens (Human)	Cytotoxic T-lymphocyte-associated antigen 4,CTLA-4
2	B, D, F, H (B, D, F, H)	4003-1(VH)	polymer	120	12891.4	4		Homo sapiens (Human)
3	I, J (B, F)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
4	K, L, M, N, O... (A, B, C, D, E...)	water	water		18.0	40	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	102243.7
Non-Polymers*	Number of molecules	2
	Total formula weight	124.1
All*	Total formula weight	102367.8

*Water molecules are not included.